Sulfadimidine acts usually bactericidal against many Gram-positive and Gram-negative microorganisms like E. coli, Staphylococcus, Streptococcus, Salmonella, Pasteurella and Eimeria spp.
Sulfadimidin affect bacterial purine synthesis, as a result of which a blockade is accomplished.
Gastrointestinal, respiratory and urogenital infections caused by sulfadimidine sensitive microorganisms like E.coli, Staphylococcus, Streptococcus and Pasteurella spp. in calves, cattle, goats, poultry, sheep and swine, and coccidiosis caused by Eimeria spp. in poultry.
Hypersensitivity to sulfonamides.
Administration to animals with a seriously impaired renal and/or hepatic function, or with blood dyscrasias.
Crystalluria, anaemia, leucopenia and thrombocytopenia.
For oral administration:
Calves, cattle,goats and sheep:
10 g per 100 kg body weight for 3 - 7 days.
1 kg per 2000 litres of drinking water for 3 - 7 days.
1 kg per 2000 litres of drinking water for 3 days, or according to the 3-2-3 scheme: 3 days on, 2 days off, 3 days on.
Note: For pre-ruminant calves, lambs and kids only.
Cattle, calves, sheep, goats: 12 days.
Poultry and swine : 15 days.
-For milk : 5 days.