Megamast LC is a suspension for intramammary administration in lactating cows. Procaine penicillin G exerts its effect on multiplying bacteria by interfering with the formation of the cell wall. Streptomycin sulphate and neomycin sulphate are both aminoglycoside antibiotics which, after penetration of the cell envelope, bind to receptors on the 30S subunit of the ribosome. They induce misreading of the genetic code on the messenger ribonucleic acid (mRNA) template, thereby inhibiting bacterial protein synthesis. Prednisolone is a glucocorticoid which has anti-inflammatory properties.
Megamast LC is indicated for treatment of acute and subacute bovine mastitis in milking cows, accompanied by pain and inflammation caused by bacterial infection sensitive to penicillin, streptomycin and neomycin therapy.
Not to be used in animals with known hypersensitivity to the active ingredients.
Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations.
Penicillins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross reactions to cephalosporins and vice versa. Allergic reaction to these substances may occasionally be serious.
For intramammary administration.
The contents of one syringe should be infused gently into each infected quarter via the teat canal immediately after milking, once daily for three consecutive days. Aseptic precautions should be observed at all times. Before infusion, the teat should be thoroughly cleaned and disinfected and care should be taken to avoid contamination of the injector nozzle. Following infusion, it is advisable to use a teat dip or spray.
- For meat: 7 days.
- For milk: 108 hours.