Meloxicam is a Non-Steroidal Anti-Inflammatory Drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, anti-exudative, analgesic and antipyretic effects. It reduces leukocyte infiltration into the inflamed tissue. To a minor extent it also inhibits collagen-induced thrombocyte aggregation. Approximately 50% of an administered dose is eliminated via urine, and the remainder via faeces.
Cattle: For use in acute respiratory infection with appropriate antibiotic therapy to reduce clinical signs in cattle. For use in diarrhoea in combination with oral re-hydration therapy to reduce clinical signs in calves of over one week of age and young, non-lactating cattle. For adjunctive therapy in the treatment of acute mastitis, in combination with antibiotic therapy. For the relief of post-operative pain following dehorning in calves.
Pigs: For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation. For adjunctive therapy in the treatment of puerperal septicaemia and toxaemia (mastitis-metritis-agalactia syndrome) with appropriate antibiotic therapy.
Horses: For use in the alleviation of inflammation and relief of pain in both acute and chronic musculo-skeletal disorders. For the relief of pain associated with equine colic.
Do not use in horses less than 6 weeks of age.
Do not use in animals suffering from impaired hepatic, cardiac or renal function and haemorrhagic disorders, or where there is evidence of ulcerogenic gastrointestinal lesions.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
For the treatment of diarrhoea in cattle, do not use in animals of less than one week of age.
Do not use in pregnant or lactating mares.
Do not administer concurrently with glucocorticosteroids, other non-steroidal anti-inflammatory drugs or with anticoagulant agents. Do not mix Intercam-20 with other veterinary medicinal products.
Avoid use in very severely dehydrated, hypovolaemic or hypotensive animals which require parenteral rehydration, as there may be a potential risk of renal toxicity. In case of inadequate relief of pain when used in the treatment of equine colic, careful re-evaluation of the diagnosis should be made as this could indicate the need for surgical intervention.
In cattle and pigs, only a slight transient swelling at the injection site following subcutaneous administration may be observed. In horses, a transient swelling at the injection site can occur but resolves without intervention. In very rare cases anaphylactoid reactions, which may be serious (including fatal), may occur and should be treated symptomatically.
To obtain adequate pain relief during dehorning procedures in calves, co-medication with an appropriate analgesic is needed.
Cattle: Single SC or IV injection at a dosage of 0.5 mg meloxicam/kg bodyweight (i.e. 2.5 ml/100 kg body weight) in combination with antibiotic therapy or with oral re-hydration therapy, as appropriate.
Pigs: Single IM injection at a dosage of 0.4 mg meloxicam/kg bodyweight (i.e. 2.0 ml/100 kg body weight) in combination with antibiotic therapy, as appropriate (can be repeated once after 24 h, if necessary).
Horses: Single IV injection at a dosage of 0.6 mg meloxicam/kg bodyweight (i.e. 3.0 ml/100 kg body weight).
Cattle: Meat and offal: 15 days; Milk: 5 days (120 hours)
Pigs: Meat and offal: 5 days.
Horses: Meat and offal: 5 days.
Not authorised to use in horses producing milk for human consumption.