Dimoxan WS

Colistin & Amoxycillin water-soluble powder

Powder for oral administration

  • Composition
  • Contains per gram powder:
  • Colistin sulphate
    1200000 IU.
  • Amoxycillin trihydrate
    200 mg.
  • Excipients ad
    1 g.

Description

The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broadspectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The spectrum of amoxycillin includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis.
Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.

Indications

Gastrointestinal, respiratory and urinary tract infections caused by amoxicillin and colistin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.

Contra indications

Hypersensitivity to amoxicillin and/or colistin.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbial digestion.

Side effects

Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.

Dosage

For oral administration:

 

Calves, goats and sheep:
Twice daily 5 g per 100 kg body weight for 3 - 5 days.

 

Poultry and swine:
1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.

 

Note: for pre-ruminant calves, lambs and kids only.

 

Please note: Before adding to the drinking water make a presolution of 1 kg Dimoxan WS per 20 litres of water with a temperature of 40 °C.

Withdrawal times

- For meat: 8 days.

Packaging

Sachet of 100 g and jar of 1000 g.
  • Calves
  • Pigs
  • Lambs
  • Poultry

Product Code:

WAC
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