Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gramnegative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Gastrointestinal infections caused by colistin sensitive bacteria, like E. coli, Haemophilus and Salmonella spp. in calves, goats, poultry, sheep and swine.
Hypersensitivity to colistin.
Administration to animals with a seriously impaired renal function.
Administration to animals with an active microbial digestion.
Renal dysfunction, neurotoxicity and neuromuscular blockade may occur.
For oral administration:
Calves, goats and sheep:
Twice daily 5 g per 100 kg body weight for 5 - 7 days.
Poultry and swine:
1 kg per 1000 - 2000 litres of drinking water or 500 - 1000 kg of feed for 5 - 7 days.
Note: for pre-ruminant calves, lambs and kids only.
- For meat : 7 days.