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Introflor-100 Oral. Solution for oral administration

Introflor-100 Oral

Solution for oral administration

Description

Florfenicol is a synthetic broad-spectrum antibiotic that is effective against most Gram-positive and Gram-negative bacteria isolated from domestic animals. Florfenicol, a fluorinated derivative of chloramphenicol, acts by inhibiting protein synthesis at the ribosomal level and is bacteriostatic. Florfenicol does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, and also has activity against some chloramphenicol-resistant strains of bacteria.

Composition

Contains per ml:
Florfenicol  100 mg.
Excipients ad  1 ml.

Indications

Introflor-100 Oral is indicated for preventive and therapeutic treatment of gastrointestinal and respiratory tract infections, caused by florfenicol sensitive micro-organisms such as Actinobaccillus spp. Pasteurella spp. Salmonella spp. and Streptococcus spp. in swine and poultry. The presence of the disease in the herd should be established before preventive treatment. Medication should be initiated promptly when respiratory disease is diagnosed.

Contra indications

Not to be used in boars intended for breeding purposes, or in animals producing eggs or milk for human consumption.
Do not administer in cases of previous hypersensitivity to florfenicol.
The use of Introflor-100 Oral during pregnancy and lactation is not recommended.
The product should not be used or stored in galvanized metal watering systems or containers.

Side effects

A decrease in food and water consumption and transient softening of the faeces or diarrhoea may occur during the treatment period. The treated animals recover quickly and completely upon termination of treatment.
In swine, commonly observed adverse effects are diarrhoea, peri-anal and rectal erythema/oedema and prolapse of the rectum. These effects are transient.

Dosage

For oral administration. The appropriate final dosage should be based on the daily water consumption.
Swine: 1 litre per 1000 litres of drinking water (100 ppm; 10 mg/kg body weight) for 5 days.
Poultry: 1 litre per 1000 litres of drinking water (100 ppm; 10 mg/kg body weight) for 3 days.

Withdrawal times

- For meat:
Swine : 21 days.
Poultry : 7 days.

Warning

Keep out of reach of children.

Packing

Bottle of 500 and 1000 ml.
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