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Penstrep-400. Suspension for parenteral use

Penstrep-400

Suspension for parenteral use

Description

The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Clostridium, Corynebacterium, Erysipelothrix, Listeria, penicillinase-negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Campylobacter, Klebsiella, Haemophilus, Pasteurella and Salmonella spp.

Composition

Contains per ml.:
Procaine penicillin G  200 000 IU.
Dihydrostreptomycin sulphate  200 mg.
Solvents ad.  1 ml.

Indications

Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.

Contra indications

Hypersensitivity to penicillins, procaine and/or aminoglycosides.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.

Side effects

Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.
Ototoxity, neurotoxicity or nephrotoxicity.
Hypersensitivity reactions.

Dosage

For intramuscular administration:
Cattle : 1 ml per 20 kg body weight for 3 days.
Calves, goats, sheep and swine : 1 ml per 10 kg body weight for 3 days.

Shake well before use and do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, sheep and goats per injection site.

Withdrawal times

- For kidney: 45 days.
- For meat: 21 days.
- For milk: 3 days.

Warning

Keep out of reach of children.

Packing

Vial of 50 and 100 ml.
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