Dimoxan WS
Powder for oral administration.Description
The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broad-spectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The range of effect includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis. Amoxycillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Composition
| Contains per gram powder: |
| Colistin sulphate | 1 200 000 IU. |
| Amoxycillin trihydrate | 200 mg. |
| Carrier ad. | 1 g. |
Indications
Gastrointestinal, respiratory and urinary tract infections caused by amoxycillin and colistin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp., in calves, goats, poultry, sheep and swine.
Contra indications
Hypersensitivity to amoxycillin and/or colistin.
Administration to animals with a serious impaired renal function.
Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbiological digestion.
Side effects
Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.
Dosage
For oral administration:
|
|
| Calves, goats and sheep | : | Twice daily 5 gram per 100 kg. body weight for 3 - 5 days. |
| Poultry and swine | : | 1 kg. per 1000 - 2000 litre drinking water for 3 - 5 days. |
Note: for pre-ruminant calves, lambs and kids only.
Please note: Before adding to the drinking water make a presolution of 1 kg. Dimoxan WS per 20 litres water with a temperature of 40 degrees Celsius.
Withdrawal times
- For meat : 8 days.
Warning
Keep out of reach of children.
Packing
Sachet of 100 gram and jar of 500 & 1000 gram.
